A variety of nanoparticles (NPs) have been synthesized using the cage protein apoferritin and Listeria ferritin. Metal oxide NPs (Co, Ni, and Cr) and semiconductor NPs (CdSe and ZnSe) were described to be made by using apoferritin with a 7 nm diameter inner cavity. The synthesized NPs show small-size dispersion, which is ideal for use as a nanoelectronic device component. There are many kinds of protein cages suitable as biotemplates, and researchers have been searching for new biotemplates with an inner cavity. Larger or smaller cage-shaped proteins have been used as biotemplates and the mechanism of biomineralization has been studied. Recent works concerning the synthesis of NPs using supra-molecular protein cages are reviewed. The applications of NPs made using biotemplates are also introduced.

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