For Biocompatible Coverage

Multilayer assemblies of natural polyions, such as DNA, polynucleotides, polylysine, and polysaccharides (e.g., hep-arin, chondroitine, and chitosan) are interesting for biological and medical applications. DNA and polynucleotides (polyuridylic and polyadenylic acids) can be readily assembled in alternation with polycations (PEI, PAH, polylysine). The assembly of polysaccharides with oppositely charged polyions is possible as a means of biocompatible surface preparation. A chitosan and albumin/heparin multilayer assembly for such coatings has been developed [42-44].

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