Physical Chemical Methods

Physical-chemical methods are the processes that combine both the physical and chemical methods during the synthesis of the materials. As shown previously, there are many different methods based on the physical or chemical principles from which lot of the physical-chemical methods could be developed. For instance, it has been shown that, as a "bottom up" process, mechanochemical processing enables the build up of nanoparticles through solid-state chemical reaction in a microscopically uniform environment, leading to the formation of nanoparticles with narrow size distributions. The physical fields, like electric fields, magnetic fields, lights, etc., could be used to affect the chemical reactions and the processes. Coacervation-phase separation has been proved to be one powerful technique for preparation of the nanocapsules. In the following, we only introduce in detail the coacervation-phase separation and briefly other physical-chemical processes.

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