Lessons in Innovation and Commercialization from the Biotechnology Revolution

We shape our tools and forever after, they shape us. Marshall McLuhan Chemistry in many forms is a major force shaping the modern world. It is the fundamental science of materials, providing everything from the tools we use to the medicines we take. Silicon and germanium enabled integrated circuits, hydrogen and oxygen propelled us into space, and recombinant DNA brought new drugs and pest-resistant crops. Yet for all these benefits, chemistry is both a misunderstood, and in many ways an...

Look Forward Think Backward What Does an Entrepreneur Do

To be realized, a vision requires time, energy, capital, belief, and drive. It is not enough to talk it is as important to lead and do. Some people look at where they are and what they have in order to see where they can go (that is, they look forward and think forward). Others see where they want to go and look at what they need to get there (they look forward and think backward). The two approaches sound similar but in fact are very different. The former is limited to using whatever resources...

Daniel V Leff

Prior to joining Harris & Harris Group, Leff was a Senior Associate with Sevin Rosen Funds in the firm's Dallas, Texas, office, where he focused on early-stage investment opportunities in semiconductors, components, and various emerging technology areas. While at Sevin Rosen Funds, he played an integral role in the funding of Nanomix, InnovaLight, Sana Security, and D2Audio. Leff has also worked for Redpoint Ventures in the firm's Los Angeles office. In addition, he previously held...

Larry Gilbert

Lawrence Gilbert is the Senior Director of Technology Transfer of Caltech, the California Institute of Technology. The Office of Technology Transfer (OTT) provides a service to Caltech faculty members, other Caltech researchers, and Jet Propulsion Laboratory (JPL) technologists by protecting the intellectual property developed in their Caltech and JPL labs. The OTT fosters the commercial development of Caltech technologies in companies ranging from local start-ups to large, multinational firms....

The Holy Grail

The greatest discovery of them all may be the process that guides us through the evolution of science to product, especially one that is capable of taking advantage of a great business opportunity. Our hopes in this regard form on two points of view the science and the business. From the technology point of view there is a tendency to hope that after the application of the technology to an existing problem, a business will pull the technology forward through the remaining commercialization...

Charles Berman

Charles Berman is a principal shareholder with the law firm Greenberg Traurig, LLP, in Santa Monica, California, and he is Co-Chair of the national patent prosecution practice of the firm. He has been active in all areas of intellectual property law for more than 35 years. He has been practicing in Los Angeles since 1978, and practiced in South Africa prior to that time. He has also worked with European patent attorneys. Berman has extensive IP experience in the United States and foreign...