DNA Nanovaccines Using Nanocapsules and Ultrasound Methods

The USDA is completing trials on a system for mass vaccination offish in fishponds using ultrasound. Nanocapsules containing short strands of DNA are added to a fishpond where they are absorbed into the cells of the fish. Ultrasound is then used to rupture the capsules, releasing the DNA and eliciting an immune response from the fish. This technology has so far been tested on rainbow trout by Clear Springs Foods (Idaho, US)—a major aquaculture company that produces about one-third of all U.S. farmed trout.

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