Nanoparticles Break Down Blood Clots

Strokes and other kinds of heart attacks are also caused by the formation of blood clots in the circulatory system. Blood clots can lead to a range of serious medical conditions, including heart attacks, pulmonary embolisms, and strokes. The main component of a clot is the insoluble fibrin. Fibrin is a blood-clotting protein and has a role in normal and abnormal clot formation (coagulation) in the body.

One research group is experimenting with different ways of treating fibrin. One test involves the use of nanoparticle drugs that dissolve and break up the fibrin. Preventing blood clots reduces the risk of stroke, heart attack, and pulmonary embolism.

Another research team is experimenting with a cardiovascular method that employs specially made molecules called "nanolipoblock-ers." The nanolipoblockers prevent cholesterol from causing inflammation and plaque buildup at specific blood vessel areas in the body.

In preliminary tests, these molecules show good results against harmful cholesterol.

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