Concluding Remarks

It is essential to understand the molecular mechanisms involved in nanoparticle-mediated drug or gene delivery to explore their therapeutic potentials for cancer therapy. Also, the important questions we need to address are: What are the barriers in targeted cancer drug therapy? What is the efficiency of drug targeting with carrier systems? Can it provide a therapeutic dose of the drug in the tumor tissue? How long should the drug effect in the tumor tissue be sustained to regress it completely? Is a combination of drugs, especially those that work by different pathways, more effective than single-drug therapy? These and other questions are critical as we move from a conceptual stage to reality. With better understanding of molecular targets, discovery of more potent drugs and simultaneous developments in nanotechnology it seems that an effective cancer therapy is forthcoming.

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