13.1 Introduction 231

13.2 Polymeric Nanoparticles 232

13.3 Nanoparticles for Drug Delivery 233

13.4 Nanoparticles for Gene Delivery 233

13.5 Long-Circulating Nanoparticles 234

13.6 Illustrative Examples of Polymeric Nanoparticles for Drug Delivery 235

13.6.1 Polyethylene Oxide-Modified Poly(ß-Amino Ester) Nanoparticles 235

13.6.2 Poly(Ethylene Oxide)-Modified Poly(s-Caprolactone) Nanoparticles 236

13.7 Illustrative Examples of Polymeric Nanoparticles for Gene Delivery 237

13.7.1 Polyethylene Glycol-Modified Gelatin Nanoparticles 237

13.7.2 Polyethylene Glycol-Modified Thiolated-Gelatin Nanoparticles 238

13.8 Concluding Remarks 238

Acknowledgments 239

References 239

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