In Vivo Targeted Drug Delivery

System Method

EPR (prolongation of circulating) Sphingomyelin modification

PEG modification Asialoglycoprotein receptor mediated Galactose modification

Target Tissue (Cell)



Mannose receptor mediated

Mannose modification

Liver (hepatocyte)

Liver (non-parenchymal cell)


45 53

59 62

64 61

66 67 71

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