Proteinrejecting Abilities Of Polyethylene Glycol Coatings

A great effort has been devoted toward suppressing the adsorption of opsonins at the particles' surface. For this, polymers were covalently bound or adsorbed on surfaces. Among these, poly(ethylene glycol) (PEG) is distinguished as one of the most commonly used polymer for surface modification [2, 24, 25]. This uncharged polyether was reported to have unlimited water solubility at room temperature [24]. In water, the high degree of hydration and large excluded volume induce repulsive forces, advantageous for surface sterical stabilization and protein repulsion.

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