Inflammation 11 Introduction

When an implant is inserted, some biological reactions take place near the implanted area. This is the body's response to this newly implanted foreign material. A successful orthopedic implant promotes the adhesion of osteoblasts on the implant surface and the formation of new bone tissue, incorporating the implant into the body. However, if the body encapsulates the implant by the formation of soft fibrous tissue and tries to separate it as much as possible from surrounding bone, this is the sign of an unsuccessful implantation. The overall aim for numerous medical devices is to minimize the amount of fibrous tissue formation around the implant and to maximize appropriate new tissue growth.

School of Engineering, Brown University, 182 Hope Street, Providence, RI 02917, USA

e-mail: [email protected]

T.J. Webster (ed.), Nanotechnology Enabled In situ Sensors for Monitoring Health, 61

DOI 10.1007/978-1-4419-7291-0_3, © Springer Science+Business Media, LLC 2011

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