Monitoring Inflammation and Infection via Implanted Nanosensors

Batur Ercan, Nhiem Tran, and Thomas J. Webster

Abstract Sensors are being used for a wide range of applications. Some of the most intriguing applications are those that involve detecting infection and inflammation. This chapter covers some fundamentals of medical device infection as well as inflammation and how sensors are being used to detect such events. It is hoped that such sensors would detect bacteria presence before infection sets in and then indicate to a clinician that such infection has occurred. It is also hoped that sensors will be able to determine early events in inflammation to avoid chronic inflammation that has plagued numerous medical devices. This chapter summarizes such advances.

Keywords Inflammation • Infection • Nanotechnology • Sensors • Drug delivery

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