Molecular molding

In this method, a highly cross-linked polymer is synthesized in the presence of a template molecule. A template, here, is a molecule whose specific geometry controls growth, structure, and configuration of the system being built up. The functional groups of the monomer bind to those of the template and lead to a replication of its outer shape. Subsequently, the template molecules are removed by extraction. Vacancies with binding sites having a defined spatial arrangement are left in the polymeric network thus formed. The guest molecule that is to be selected is structurally similar or identical to the template and can be molecularly recognized and bound. Using this method it is possible, for example, to isolate individual molecules from a mixture (IGVT 2003).

0 0

Post a comment