Unquestionably, nanoparticles possess some of the most potent biological activities ever described. The potential benefits of nanotechnology are therefore immense. However, these attributes make it even more obligatory that the risks inherent in the use of such potent biofactors, particularly in foods, aerosols, cosmetics and skin lotions/creams, must be rigorously assessed before their commercialization. Accordingly, and as first step, a nutritional protocol is presented in this chapter for the safety testing of the nanoparticles that have already been or are likely to be incorporated in future into human foods even though, judging by the near absence of published articles in peer-reviewed journals, this was apparently done without appropriate safety testing.

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